Ratiometric Iridium(III) Complex-Based Phosphorescent Chemodosimeter for Hg2+ Applicable in Time-Resolved Luminescence Assay and Live Cell Imaging
作者： Jiaxi Ru , Xu Chen , Liping Guan , Xiaoliang Tang , Chunming Wang
DOI: 10.1021/AC503878S
关键词: Ion 、 Iridium 、 Photochemistry 、 Live cell imaging 、 Fluorescence 、 Photoluminescence 、 Luminescence 、 Chemistry 、 Phosphorescence 、 Density functional theory
摘要: A novel iridium(III) complex-based probe Ir4-1 has been designed and synthesized conveniently by incorporating the chemodosimeter into phosphorescent luminophor, which displayed ratiometric luminescence change from yellowish-green to reddish-yellow only toward Hg2+ ions in aqueous media via desulfurization intramolecular cyclization with a broad pH range of 5–10. The could eliminate effectively signal interference short-lived fluorescent background, signal-to-noise ratio detection was improved distinctly using time-resolved photoluminescence technique. Furthermore, mechanism phosphoresce analyzed detail time-dependent density functional theory (TD-DFT) calculations, long-wavelength emission be applied label cells monitor intracellular imaging.
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