Vaginal matrices: nanofibers for contraception and prevention of hiv infection

作者: Anna Blakney , Cameron Ball , Emily Krogstad , Kim A. Woodrow , Huarong Nie

DOI:

关键词: Human immunodeficiency virus (HIV)Targeted drug deliveryDrug deliveryNanofiberElectrospinningMaterials sciencePharmacologyDrug/agentDrugBiomedical engineeringPharmacokinetics

摘要: Described are drug delivery systems incorporating electrospun fibers that comprise and deliver physicochemically diverse compounds. Such provide significant advantages in agent release, such as adaptability for solid dosage to mucosal tissues. This is addition allowing controlled release. Systems methods large-scale electrospinning productivity described, including novel microarchitectures variable pharmacokinetics

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