Use of allogenic or syngenic major histocompatibility complex (MHC) molecules as universal adjuvants for vaccines against neoplastic disease, infection and autoimmune disease
作者： Moriya Tsuji
DOI:
关键词: Stimulation 、 Inflammation 、 Major histocompatibility complex 、 Biology 、 Antigen 、 Immunology 、 Adjuvant 、 Autoimmune disease 、 Antigen presentation 、 Syngenic
摘要: The present invention is directed to the discovery that allogenic or syngenic adjuvant stimulation can cause local inflammation which increases antigen presentation capability of cells in vicinity stimulation. By discovering this phenomenon, provides a novel method for augmenting immunogencity an by conjointly administering MHC molecule (as universal adjuvant) trigger inflammatory reaction enhance at site delivery.
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