Green synthesis of silver nanoparticles at low temperature in a fast pace with unique DPPH radical scavenging and selective cytotoxicity against MCF-7 and BT-20 tumor cell lines.

摘要: "Black Peel Pomegranate" is a rare pomegranate cultivar that its specific features are still uncovered particularly in the bio-nano researches. The present study was organized to evaluate this pomegranate's potential biosynthesis of silver nanoparticles as well bio-medical activities. According results, peel extract incredibly inhibited 100 % DPPH free radicals (EC50 = 5 μg/mL). This also induced more than 70 cell death treated breast tumor lines, BT-20 and MCF-7. Interestingly, capable very stable small (15.6 nm) at ambient temperature an ultra-fast pace. Likewise, these 77 (EC50 = 9 μg/mL). Although antioxidant capacity lower extract, instead, anticancer activity synthesized significantly enhanced, so they led 81 89 lines MCF-7, respectively. Considerably, neither nor biosynthesized nanoparticles, showed significant toxicity against non-tumor (L-929) same concentrations. These were quite outstanding comparison with chemical/commercial ones. Overall, introduces black worthy bio-agent unique activities cancer treatment.