Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells.
作者： Ivan Tattoli , Catherine J. Streutker , Catherine J. Streutker , Ken Cadwell , Dana J. Philpott
DOI: 10.1016/J.CELREP.2020.108677
关键词: Immunosuppression 、 Reprogramming 、 NOD1 、 Cancer 、 Colorectal cancer 、 Tumor progression 、 Cancer research 、 Medicine 、 Autophagy 、 Phenotype
摘要: … of MDSCs and tumor-associated macrophages in cancer, we … Nod1 detection, modulate the immunosuppressive activity of … the classical pharmacological inhibitor, chloroquine (CQ) (…
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