Randomized controlled trials covering pharmaceutical care and medicines management: A systematic review of literature.

作者: Zaheer-Ud-Din Babar , Rozina Kousar , Ghulam Murtaza , Saira Azhar , Shujaat Ali Khan

DOI: 10.1016/J.SAPHARM.2017.06.008

关键词: Depression (differential diagnoses)MEDLINEPharmaceutical careRandomized controlled trialIntensive care medicinePsychiatryDiabetes mellitusPatient educationJadad scalePsychological interventionMedicine

摘要: Abstract Objective To review the effects of pharmaceutical care on hospitalizations, mortality and clinical outcomes in patients. Methods Systematic searches were conducted MEDLINE, EMBASE International Pharmaceutical Abstracts (IPA) databases to identify studies that published between 2004 January 2017. Studies included this randomized controlled trials (RCTs) spanned across both community hospital settings. Using strict inclusion/exclusion criteria if they reported level 1 or 2 hierarchy outcome measure i.e. surrogate (e.g. blood pressure (BP) control, glucose level, cholesterol BMI). Each study was assessed for quality using Jadad scoring system. Results Fifty-four RCTs present review. Forty-six these ranked high according categorized into their general condition groups. Interventions patients with diabetes, depression, respiratory disorders, cardiovascular epilepsy, osteoporosis, interventions older adults identified. In majority found lead significant improvements and/or hospitalizations when compared non-intervention group. Some conditions had a large number RCTs, example diabetes. Statistically seen conditions, indicating positive rates. Within condition, subset studies, focusing cardiac heart failure coronary disease, more mixed results. other small evidence did not show after care, epilepsy. The face interactions patients, whilst smaller via telephone one web-based Patient education key component most interventions, either verbal written. Longitudinal data, post intervention cessation, collected cases. Conclusions evaluate appear be effective improving patient short-term including diabetes however, such as depression are less well researched. Future research should attempt where there is lack whether persist populations cease what long-term would continued care.

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