Virologic and Serologic Studies on Human Products of Conception after Maternal Rubella

作者: Charles A. Alford , Franklin A. Neva , Thomas H. Weller , Louise S. Kanich , Linda M. Giraldi

DOI: 10.1056/NEJM196412172712501

关键词: FetusFetal damageProducts of conceptionVirologyRubella virusImmunologyCongenital RubellaRubellaMedicinePregnancySerology

摘要: ALTHOUGH the teratogenic potential of rubella virus was established by Gregg1 in 1941 pathogenesis fetal damage associated with maternal rubella, necessity, has remained ill defined. The recent development procedures for propagation laboratory2 , 3 permits virologic and serologic investigation congenital infections. Already, been recovered from an aborted human fetus.4 Furthermore, it is that infection does not result a state immunologic tolerance5 6; such may induce persistent antibody response permit retrospective diagnosis . . .

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