作者: Charles A. Alford , Franklin A. Neva , Thomas H. Weller , Louise S. Kanich , Linda M. Giraldi
DOI: 10.1056/NEJM196412172712501
关键词: Fetus 、 Fetal damage 、 Products of conception 、 Virology 、 Rubella virus 、 Immunology 、 Congenital Rubella 、 Rubella 、 Medicine 、 Pregnancy 、 Serology
摘要: ALTHOUGH the teratogenic potential of rubella virus was established by Gregg1 in 1941 pathogenesis fetal damage associated with maternal rubella, necessity, has remained ill defined. The recent development procedures for propagation laboratory2 , 3 permits virologic and serologic investigation congenital infections. Already, been recovered from an aborted human fetus.4 Furthermore, it is that infection does not result a state immunologic tolerance5 6; such may induce persistent antibody response permit retrospective diagnosis . . .