Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.
作者： X Wang , Y-X Zhou , W Qiao , Y Tominaga , M Ouchi
关键词: Cancer research 、 Protein kinase B 、 Carcinogenesis 、 Sister chromatid segregation 、 Mammary tumor 、 Mammary tumor virus 、 Biology 、 Cell cycle 、 Malignant transformation 、 PI3K/AKT/mTOR pathway
摘要: Abstract Aurora-A/STK15/BTAK, which encodes a centrosome-associated kinase, is amplified and overexpressed in multiple types of human tumors, including breast cancer …
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