A case of malignant transformation in thoracic vertebral hemangioma following repetitive irradiation and extraction.
作者： Yasuro Obana , Kurenai Tanji , Itaru Furuta , Toshiaki Yamazumi , Shigeo Hashimoto
DOI: 10.1111/J.1440-1827.1996.TB03536.X
关键词: Positive staining 、 Malignant transformation 、 Angiosarcoma 、 Medicine 、 Hemangioma 、 Surgery 、 Vertebral hemangioma 、 Pathology 、 Radiology 、 Radiation therapy 、 Clinical course 、 Hemangiosarcoma
摘要: We report a rare case of thoracic vertebral hemangioma which developed into angiosarcoma during the course repetitive operations and irradiation. A 44 year old female was operated on for first vertebra. The diagnosis confirmed histo-pathologically with specimen from operation. tumor multiple lesions later in clinical after operation, these were removed four consecutive each histologlcai that hemangioma. Throughout period operations, patient treated wtih steroid, radiotherapy simultaneously. underwent fifth operation recurrence 26 March 1990, histopathological not but hemangiosarcoma considered malignant transformation. cells immunohistochemically revealed positive staining UEA-I, Factor-VIII, as showed vascular endothe-lioid nature.
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