Adoption studies on psychiatric illness : epidemiological, environmental and genetic aspects

摘要: The aim of this study is to evaluate the outcome adoptions and gene-environment influences on psychiatric illness as well sick-leave patterns. material consists 2 966 adopted persons born between 1917 1949, their 5 932 adoptive parents 438 identified biological parents.Adopted had a higher incidence personality disorders substance abuse than non-adopted controls. Adopted men also an increased neuroses. women because somatic complaints, especially upper respiratory tract infections abdominal complaints short duration. Somatization i.e. more sick-leaves/year complaint together with nervous was frequent among women. Women somatization could be separated into types according pattern sick-leave. Type 1 ("high frequency") sick-leaves for psychiatric, back complaints. They high frequency alcohol abuse. ("diversiform") diverse fewer complaints.High somatizers fathers teenage onset criminality registrations Diversiform same genetic background petty or male limited alcoholism.No specific treated depression were found in study. However, non-specific vulnerability mother influenced risk women.There some indications that placement home 6 12 months age associated reactive neurotic adult life. Otherwise early negative experiences term unstable placements before adoption did not significantly influence adulthood.Affective father treatment depressions adoptee. Low social status part both