International Union of Pharmacology. LV. Nomenclature and Molecular Relationships of Two-P Potassium Channels

作者: Steve A. N. Goldstein , Douglas A. Bayliss , Donghee Kim , Florian Lesage , Leigh Daniel Plant

DOI: 10.1124/PR.57.4.12

关键词: Potassium channelChemistryInward-rectifier potassium ion channelPharmacologyK2p channelCellular excitabilityPotassiumPotassium ionsMembrane potential

摘要: In less than a decade since their discovery, the study of K2P channels has revealed that background leak potassium ions via dedicated pathways is highly regulated mechanism to control cellular excitability. Potassium pathways, active at rest, stabilize membrane potential below firing

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