作者: Steve A. N. Goldstein , Douglas A. Bayliss , Donghee Kim , Florian Lesage , Leigh Daniel Plant
DOI: 10.1124/PR.57.4.12
关键词: Potassium channel 、 Chemistry 、 Inward-rectifier potassium ion channel 、 Pharmacology 、 K2p channel 、 Cellular excitability 、 Potassium 、 Potassium ions 、 Membrane potential
摘要: In less than a decade since their discovery, the study of K2P channels has revealed that background leak potassium ions via dedicated pathways is highly regulated mechanism to control cellular excitability. Potassium pathways, active at rest, stabilize membrane potential below firing