Synthesis of FinP RNA by plasmids F and pSLT is regulated by DNA adenine methylation.

作者: Joaquín Torreblanca , Josep Casadesús , Silvia Marqués

DOI: 10.1093/GENETICS/152.1.31

关键词: Molecular biologyAntisense RNAMethylationPlasmidVirulenceBiologyDNA methylationGeneticsDNAEscherichia coliRNA

摘要: DNA adenine methylase mutants of Salmonella typhimurium contain reduced amounts FinP, an antisense RNA encoded by the virulence plasmid pSLT. Lowered FinP levels are detected in both Dam- FinO+ and FinO- backgrounds, suggesting that Dam methylation regulates production rather than half-life. Reduced F-encoded likewise found Escherichia coli. A consequence scarcity absence is S. E. coli show elevated F transfer. Inhibition fertility also impaired a background.

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