Malaria: Host-Pathogen Biology

摘要: The development of resistance to insecticides by anopheline mosquito vectors malaria and drugs Plasmodium falciparum pose new challenges for control programs. establishment methods the continuous cultivation in vitro plasmodia provided an important tool research into cellular biology metabolism these parasites. molecular basis parasite's attachment entry erythrocytes host is being elucidated. impact intracellular parasite on erythrocyte explored, recognition role as oxidant stress suggested a certain forms genetic malaria. In addition, consequences parasitization are studied with regard alterations antigenicity, rheologic properties, transport nutrients antimalarial drugs. host's immune response assessed both protective immunosuppressive effects. rapid accumulation knowledge host-parasite could provide design novel pharmacologic immunologic