3D Direct Printing of Silicone Meniscus Implant Using a Novel Heat-Cured Extrusion-Based Printer.

作者: Eric Luis , Houwen Matthew Pan , Swee Leong Sing , Ram Bajpai , Juha Song

DOI: 10.3390/POLYM12051031

关键词: Composite materialExtrusionMolding (process)ImplantRheologyCasting (metalworking)Materials science3D printingSilicone resinSilicone

摘要: The first successful direct 3D printing, or additive manufacturing (AM), of heat-cured silicone meniscal implants, using biocompatible and bio-implantable resins is reported. Silicone implants have conventionally been manufactured by indirect casting molding methods which are expensive time-consuming. A novel custom-made heat-curing extrusion-based printer capable directly printing medical introduced. rheological study the optimization critical process parameters described in detail. surface cross-sectional morphologies printed meniscus implant were also included. time-lapsed simulation heated resin within nozzle computational fluid dynamics (CFD) was done results obtained closely resembled real time printing. Solidworks one-convection model simulation, when compared to on-off model, more correlated with actual probed temperature. Finally, comparative mechanical between heat-molded conducted. opens up opportunities for rapid various customizable devices patients fills current gap industry.

参考文章(27)
Weimin Guo, Shuyun Liu, Yun Zhu, Changlong Yu, Shibi Lu, Mei Yuan, Yue Gao, Jingxiang Huang, Zhiguo Yuan, Jiang Peng, Aiyuan Wang, Yu Wang, Jifeng Chen, Li Zhang, Xiang Sui, Wenjing Xu, Quanyi Guo, Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration. Stem Cells International. ,vol. 2015, pp. 517520- 517520 ,(2015) , 10.1155/2015/517520
Todd A. Bullions, J. E. McGrath, A. C. Loos, Development of a two‐stage, dual‐Arrhenius rheology model for a high‐performance phenylethynyl‐terminated poly(etherimide) Polymer Engineering and Science. ,vol. 42, pp. 2182- 2192 ,(2002) , 10.1002/PEN.11108
Francois B. Mazas, &NA; Guepar, Guepar total knee prosthesis. Clinical Orthopaedics and Related Research. ,vol. 94, pp. 211- 221 ,(1973) , 10.1097/00003086-197307000-00026
Donna E. Foliart, Swanson silicone finger joint implants: A review of the literature regarding long-term complications Journal of Hand Surgery (European Volume). ,vol. 20, pp. 445- 449 ,(1995) , 10.1016/S0363-5023(05)80104-2
Saakshi Dhanekar, Swati Jain, Porous silicon biosensor: current status. Biosensors and Bioelectronics. ,vol. 41, pp. 54- 64 ,(2013) , 10.1016/J.BIOS.2012.09.045
Tatsuhiro Takahashi, Joachim Kaschta, Helmut Münstedt, Melt rheology and structure of silicone resins Rheologica Acta. ,vol. 40, pp. 490- 498 ,(2001) , 10.1007/S003970100173
Nadia El Kissi, J. M. Piau, P. Attané, G. Turrel, Shear rheometry of polydimethylsiloxanes. Master curves and testing of Gleissle and Yamamoto relations Rheologica Acta. ,vol. 32, pp. 293- 310 ,(1993) , 10.1007/BF00434194
W. L. Robb, Thin Silicone Membranes-Their Permeation Properties and Some Applications Annals of the New York Academy of Sciences. ,vol. 146, pp. 119- 137 ,(1968) , 10.1111/J.1749-6632.1968.TB20277.X