作者: Robert A. McNutt , Gary S. Ferenchick , Philip C. Kirlin , Nancy J. Hamlin
DOI: 10.1016/0002-9149(88)91390-2
关键词: Creatine kinase 、 Cholesterol 、 Internal medicine 、 Anabolic steroid 、 Myocardial infarction 、 Medicine 、 Anabolism 、 Cardiology 、 Low-density lipoprotein 、 High-density lipoprotein 、 Chest pain
摘要: A major concern facing the medical profession in dealing with athletes is widespread use of anabolic steroids despite no proof their effectiveness on athletic prowess.* Elevated circulating levels low density lipoprotein (LDL) cholesterol and lowered high (HDL) have recently been reported powerlifters using steroids.2 Therefore, steroid resultant unfavorable lipid profiles may increase risk cardiovascular disease. We report a case world class powerlifter who presented acute myocardial infarction, marked hypercholesterolemia an abnormal LDL/HDL ratio. The clinical circumstances suggest causal relationship to use. 22-year-old, 330~pound male, power weightlifter past or family history cardiac diseases was admitted severe chest pain that awakened him from sleep. patient intramuscular oral androgenic daily during 6 weeks before he developed pain. He denied cocaine Physical findings admission were normal. Laboratory studies revealed elevated creatine kinase (6,182 U/ml 15% MB band). electrocardiogram disclosed ST-segment elevations Q waves leads II, III, aVF, Vs V6. Cardiac catheterization performed 10 days after infarct demonstrated normal coronary arteries apical dyskinesia. Total serum at 596 mg/dl (LDL 513 HDL 14 mg/dl). Twenty-four