Stem Cell Ageing and Apoptosis

摘要: Ageing has been defined as the process of deterioration many body functions over lifespan an individual. In spite number different theories about ageing, there is a general consensus in identifying ageing effects reduced capacity to regenerate injured tissues or organs and increased propensity infections cancer. recent years stem cell theory gained much attention. Adult cells residing mammalian are essential for tissue homeostasis repair throughout adult life. With advancing age, highly regulated molecular signalling necessary ensure proper cellular, tissue, organ loses coordination leads, consequence, compromised potential regeneration damaged tissues. Although complete comprehension mechanisms involved apoptosis far be reached, studies beginning unravel processes particularly skeletal muscle cells, namely satellite cells. Thus, focus this review analyse relationship between with peculiar attention human compared haematopoietic Undoubtedly, knowledge age-related changes will help understanding itself provide novel therapeutic challenges improved regeneration.