Antiangiogenic and antivascular therapy for cancer.

作者: Giulia Taraboletti , Barbara Margosio

DOI: 10.1016/S1471-4892(01)00065-0

关键词: Tumor angiogenesisTumor vasculatureClinical trialCombined Modality TherapyPharmacologyOncologyMedicineCancerInternal medicineCancer biology

摘要: The great interest in the potential antineoplastic effect of targeting tumor-associated blood vessels has generated an expanding armamentarium therapeutic tools that include antiangiogenic compounds, aimed at preventing formation vessels, and antivascular targeted to existing tumor vasculature. Following promising preclinical studies, drugs have rapidly gained access clinical trials.

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