作者: Giulia Taraboletti , Barbara Margosio
DOI: 10.1016/S1471-4892(01)00065-0
关键词: Tumor angiogenesis 、 Tumor vasculature 、 Clinical trial 、 Combined Modality Therapy 、 Pharmacology 、 Oncology 、 Medicine 、 Cancer 、 Internal medicine 、 Cancer biology
摘要: The great interest in the potential antineoplastic effect of targeting tumor-associated blood vessels has generated an expanding armamentarium therapeutic tools that include antiangiogenic compounds, aimed at preventing formation vessels, and antivascular targeted to existing tumor vasculature. Following promising preclinical studies, drugs have rapidly gained access clinical trials.