Rheumatoid vasculitis: experience with 13 patients and review of the literature.

摘要: Abstract Rheumatoid vasculitis is an uncommon but potentially catastrophic complication of RA. There are few current extensive experiences and no consensus regarding the clinical, laboratory, histologic features, management or prognosis rheumatoid vasculitis. We therefore reviewed selected observations in 13 patients followed over past decade compared them with reported results a survey North American Rheumatologists. Our were seven men six women (age, 33 to 70 years) who had active RA for 4 36 years. They exhibited sensory neuropathy, mononeuritis multiplex, Felty syndrome, cutaneous lesions, leg ulcers, gangrene, anemia, leukocytosis, eosinophilia, high titers RF, hypocomplementemia, CICs cryoglobulinemia approximately as frequently other vasculitis, they displayed constitutional symptoms, subcutaneous nodules, ischemic changes, proteinuria rather less consistently than series. These not necessarily expected by respondents. We, series suggested respondents, tended select penicillamine cytotoxic drugs (or plasmapheresis) mononeuritis, nonsteroidal antiinflammatory drugs, antimalarials, gold, neuropathy digital lesions. Four died, two deteriorated, stable improved, finding that was also similar others. uncommon, syndrome varying clinicopathologic features have different prognostic implications should be managed individually.