Mathematical Modelling of Regeneration of a Tissue-Engineered Trachea
作者： Greg Lemon , John R. King , Paolo Macchiarini
关键词: Tracheal segment 、 Engineering 、 Transplantation 、 Regeneration (biology) 、 Biochemical engineering 、 Regenerative medicine 、 Tissue engineering 、 Tissue engineered 、 Tracheal lumen
摘要: One of the most promising recent achievements in field regenerative medicine was first successful transplantation a tissue-engineered trachea (Macchiarini et al. The Lancet 372(9655), 2023–2030). This land-mark operation has paved way for developing host stem cell-based therapies treating disease, and exciting possibility tissue engineering whole organs. It also provided opportunity new directions mathematical computational modelling engineering. By describing an approach to regeneration seeded with cells situ this chapter will highlight some opportunities challenges involved applying models these therapies.
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