Iron replacement therapy in the routine management of blood donors
作者： Barbara J. Bryant , Yu Ying Yau , Sarah M. Arceo , Jennifer Daniel-Johnson , Julie A. Hopkins
DOI: 10.1111/J.1537-2995.2011.03488.X
关键词: Gastrointestinal bleeding 、 Low hemoglobin 、 Ferrous 、 Surgery 、 Iron replacement 、 Medicine 、 No donors 、 Gastroenterology 、 Ferritin 、 Hematinic 、 Hemochromatosis 、 Internal medicine 、 Immunology 、 Immunology and Allergy 、 Hematology
摘要: BACKGROUND: Iron depletion or deficiency in blood donors frequently results deferrals for low hemoglobin (Hb), yet centers remain reluctant to dispense iron replacement therapy donors. STUDY DESIGN AND METHODS: During a 39-month period, 1236 deferred Hb level of less than 12.5 g/dL and 400 nondeferred control underwent health history screening laboratory testing (complete counts, studies). were defined as ferritin 9 19 9 µg/L females 18 29 18 µg/L males. Deferred iron-deficient given 60-pack 325-mg ferrous sulfate tablets instructed take one tablet daily. Another was dispensed at all subsequent visits. RESULTS: In the low-Hb group, 30 23% 8 53% males had deficiency, respectively, compared with 10% 21% group. Iron-depleted -deficient taking showed normalization iron-related parameters, even they continued donate. Compliance oral 68%. Adverse gastrointestinal effects occurred donors. The study identified 13 serious medical conditions, including eight bleeding. No malignancies hemochromatosis. CONCLUSION: found female 61% male 39% Routine administration is safe effective prevents development
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