Prediction of morbidity in small and normally grown fetuses by fetal heart rate variability, biophysical profile score and umbilical artery Doppler studies.

摘要: Objective To assess the ability of noninvasive tests fetal wellbeing to predict hypoxic morbidity independent size. Design A prospectively planned, longitudinal, observational study. Setting Fetal Surveillance Unit, King's College Hospital, London. Subjects One hundred and ninety-one pregnant women with singleton pregnancies who were delivered after 32 weeks' gestation seen in Unit within seven days delivery. Interventions surveillance by abdominal circumference, heart rate variability (mean range), biophysical profile score umbilical artery pulsatility index measurements. Main outcome measures Birthweight was classified as < or ≤2.5th centile (AGA SGA) for gestational age sex. Morbidity defined at least one following birth: delivery emergency caesarean section distress, venous blood pH less than 7.15, 5 min Apgar 7 admission Special Care Baby (SCBU). Results circumference best indicator which fetuses (n = 30) would be SGA. Fourteen 30 (47%) SGA had birth abnormal Doppler studies significantly predicted this (χ2= 2.93, P= 0.003). By contrast, did not. Twenty-seven 161 (17%) AGA birth, but not variability, studies. Conclusions None antenatal testing techniques studied normally grown indicated whether a small fetus ‘sick small’ ‘normal small’.