Derivatives of doxorubicine, their preparation and use

摘要: New derivatives of doxorubicine the formula ##STR1## wherein R represents a radical ##STR2## R1 hydrogen, alkyl (possibly substituted with amino, alkylamino, dialkylamino, hydroxy, mercapto or methylthio), phenyl, benzyl one more hydroxy) and R2 hydrogen forms an alkylene radical, salts thereof pharmaceutical compositions containing said compounds. They are prepared according to methods known in peptidic chemistry by reacting reactive form aminoacid ##STR3## doxorubicine.