The Mukaiyama reaction of ketene bis(trimethylsilyl) acetals with α-halo acetals : A convenient butenolide synthesis
作者： F.W.J. Demnitz
DOI: 10.1016/S0040-4039(01)93317-9
关键词: Lactone 、 Ketene 、 Trimethylsilyl 、 Butenolide 、 Chemistry 、 Organic chemistry 、 Acetal
摘要: Abstract Ketene bis(trimethylsilyl) acetals were reacted with α-halo giving β-alkoxy-γ-halo acids which converted to butenolides by reaction two equivalents of base. This constitutes a novel and short butenolide synthesis.
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