CNAPS in Therapy Monitoring

摘要: Monitoring of disease state and therapy response is highly relevant for efficient patient management. tools comprise observation clinical signs performing specific examinations such as imaging or blood analyses. This review focusses on the relevance blood-based biomarker monitoring by circulating nucleic acids diverse indications that exemplified patients who develop suffer from cancer disease. These include (i) screening groups have a risk to disease, (ii) local systemic therapies in with defined diagnosis (iii) early detection recurrence after primary has ended. Useful biomarkers fulfill highest methodical, pre-analytical quality criteria be implemented standardized management procedures. The current situation summarized levels genetic, epigenetic, transcript, non-coding RNA nucleosome markers an outlook presented how these can integrated into future strategy enables personalized patients.