The Reach Perspective: Toward a New Concept of Toxicity Testing

摘要: A sustainable society and a healthy are major goals for European policymakers. Although most Europeans live longer life than ever, there is growing concern anxiety about unknown health risks threats of chemicals strong demand more knowledge control. legislation responding to these demands. An example the program on Registration, Evaluation, Authorisation Restriction Chemicals (REACH), which came into force in 2007. It gigantic task industry administrators evaluate safety files thousands period 12 years collect new data not yet evaluated. Costs, number toxicity tests, animals that needed already well documented. REACH uses strict guidelines focuses apical endpoints have been covered past by animal tests. Animal tests slow, use unrealistic high doses, shown always predict human correctly. The pr...