Suppression of human choriocarcinoma maintained in the hamster cheek-pouch by extracts and alkaloids of Vinca rosea.

摘要: SummaryCrude extract of Vinca rosea as well the alkaloids, Vincaleukoblastine and Leurosine markedly inhibit growth a heterologously transplanted human choriocarcinoma in hamster cheek-pouch. The host tolerance to these agents suggests their potential clinical usefulness.The able technical assistance Messrs. Howard Erwin, Charles K. Turner, James Brice is gratefully acknowledged.