Preoperative Hypoalbuminemia is a Risk Factor for Early and Late Mortality in Patients Undergoing Endovascular Juxtarenal and Thoracoabdominal Aortic Aneurysm Repair.

作者: Max Wohlauer , Corey Brier , Yuki Kuramochi , Matthew Eagleton

DOI: 10.1016/J.AVSG.2017.03.058

关键词: HypoalbuminemiaMedicineUnivariate analysisProportional hazards modelComplicationRetrospective cohort studyOdds ratioRisk factorEndovascular aneurysm repairSurgery

摘要: Background Advances in endovascular aneurysm repair now allow surgeons to treat high-risk patients with complex aortic aneurysms. Stringent selection criteria for exist from an anatomic and technical perspective; however, there is a paucity of literature examining frailty being evaluated fenestrated branched (FEVAR). As marker well supported the literature, we hypothesized that preoperative hypoalbuminemia would increase risk short-term mortality after juxtarenal thoracoabdominal repair. Methods One thousand eighty nine consecutive aneurysms considered high open surgery single institution who underwent FEVAR 2001 2014 were included study. Risk factors all-cause identified via Cox regression model on time death. Results The severe (albumin P  = 0.025, odds ratio [OR]: 4.967 (95% CI: 1.385–17.814, normal versus severe) 2-year  = 0.006, OR: 2.4, 95% 1.05–5.73, severe), as increased 30-day complication rates  = 0.026, 1.91, 0.9–4.17, severe). A univariate analysis revealed no significant difference median age: 75.1 vs. 72.5 years (alive at 30 days (Q1, Q3: 69.8, 80.1) expired 69.3, 77.8),  = 0.24. Conclusions Patients have significantly risk. Albumin level regulated by nutritional intake inflammation due chronic disease, which make it useful part assessment. Further studies are needed to identify whether optimizing nutrition status will affect albumin levels or decrease mortality.

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