RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX

作者: Donald H Burke , Larry Gold

DOI: 10.1093/NAR/25.10.2020

关键词: Structural motifAdenosine triphosphateRNASystematic evolution of ligands by exponential enrichmentBinding siteNucleotideBiologyAptamerConserved sequenceBiochemistry

摘要: … of sequence conservation among 65 adenosine-… adenosine aptamer, we find that the most highly conserved nucleotides contact the bound adenosine directly, and that one conserved …

参考文章(1)
Petra Burgstaller, Michael Famulok, Isolation of RNA Aptamers for Biological Cofactors by In Vitro Selection Angewandte Chemie. ,vol. 33, pp. 1084- 1087 ,(1994) , 10.1002/ANIE.199410841