作者: Sandro Pignata , Carmela Pisano , Giovanni Salvatore Bruni , Gaetano Facchini , Sandro Pignata
DOI: 10.2147/TCRM.S4317
关键词: Epithelial ovarian cancer 、 Oncology 、 Surgery 、 Treatment regimen 、 Overall survival 、 Medicine 、 Mortality rate 、 Chemotherapy 、 Disease 、 Recurrent disease 、 Ovarian cancer 、 Internal medicine
摘要: Epidemiologic analysis reveals that the mortality rate from ovarian cancer is continuously decreasing due to improvement of surgery and chemotherapy. However, prognosis patients still unsatisfactory overall considering only 30% are alive after five years. In fact, although first-line systemic chemotherapy induces complete partial response in up 80% with about a 25% pathological remission rate, recurrences occur majority patients. The role recurrent disease has been recently studied many can receive an optimal secondary cytoreduction. Most subject number treatment regimens that, palliative nature, also able prolong survival. Important results have obtained particular platinum-sensitive where platinum-based progression-free survival Overall, our armamentarium for progressive or significantly richer than past, it possible achieve goal controlling chronic behavior disease.