Choroidal Thickness Changes After Photodynamic Therapy and Recurrence of Chronic Central Serous Chorioretinopathy

作者: Yong-Kyu Kim , Na-Kyung Ryoo , Se Joon Woo , Kyu Hyung Park

DOI: 10.1016/J.AJO.2015.04.011

关键词: Indocyanine greenUrologyChronic central serous chorioretinopathyTreatment outcomeSubretinal fluidVerteporfinPhotodynamic therapyFluorescein angiographySurgeryMedicineRetrospective cohort study

摘要: Purpose To investigate long-term changes in subfoveal choroidal thickness (SCT) after photodynamic therapy (PDT) and their relationship with chronic central serous chorioretinopathy (CSC) recurrence. Design Retrospective, observational, comparative case series. Methods Fifty-seven eyes CSC (52 patients, ≥2 years follow-up) treated half-fluence or half-dose PDT were divided into 2 groups: those incomplete resolution subretinal fluid (SRF) recurrence (SRF+) complete SRF absorption without disease (SRF−). The SCT was measured using spectral-domain optical coherence tomography relative ratios (follow-up SCT: baseline ratio) compared between the groups. Results Mean follow-up period 33.9 ± 9.9 months (range: 24–62 months). Four of 57 (7%) had persistent 12 53 (22.6%) initial SRF+ group a slower reduction during first month ( P Conclusions Those decline at 1 month higher ratio throughout to may reflect efficacy help predict early treatment outcomes.

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