Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus

作者: Pamela S Hair , Charlene G Echague , Reuben D Rohn , Neel K Krishna , Julius O Nyalwidhe

DOI: 10.1186/1479-5876-10-35

关键词: CytotoxicityComplement C3-C5 ConvertasesEscherichia coliMicrobiologyOpsonin ProteinsComplement systemStaphylococcal infectionsPhagocytosisBiologyImmunologyStaphylococcus aureus

摘要: Background Diabetic patients are at increased risk for bacterial infections; these studies provide new insight into the role of host defense complement system in controlling pathogens hyperglycemic environments.

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