On the terms “reticulosis” and “reticulum cell sarcoma” with regard to the modern concept of the monocyte macrophage system

作者: L. -D. Leder

DOI: 10.1007/BF01477130

关键词: Mononuclear phagocyte systemMyeloidLymphatic systemHistiocyteMonocyteHaematopoiesisPathologyBiologyMacrophageHematopathology

摘要: The terms “reticulosis” and “reticulum cell sarcoma” (= malignant lymphoma, histiocytic type) are discussed regarding the modern concept of monocyte macrophage system which today has replaced ancient theory reticuloendothelial system. is not independent, but closely related to myeloid Thus, a third blood forming as was believed in case RES does exist. Phagocytic reticulum cells various hematopoietic organs highly activated monocyte-derived macrophages. All those conditions formerly termed “reticuloses” have been found belong either or lymphatic Considering sarcomas lymphomas, most them seem be rather than origin, representing highgrade possibly immunoblastic sarcomas. No relationship between these tumours established, so far. Therefore, should no longer used order avoid confusion, stimulate sufficient diagnostic efforts will really clarify such cases, give full credit results hematopathology.

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