Impact of prescription drug monitoring programs and pill mill laws on high-risk opioid prescribers: A comparative interrupted time series analysis.

摘要: Abstract Background Prescription drug monitoring programs (PDMPs) and pill mill laws were implemented to reduce opioid-related injuries/deaths. We evaluated their effects on high-risk prescribers in Florida. Methods used IMS Health’s LRx Lifelink database between July 2010 September 2012 identify opioid-prescribing Florida (intervention state, N: 38,465) Georgia (control 18,566). The pre-intervention, intervention, post-intervention periods were: 2010–June 2011, 2011–September October 2012. High-risk those the top 5th percentile of opioid volume during four consecutive calendar quarters. applied comparative interrupted time series models evaluate policy clinical practices monthly prescribing measures for low-risk/high-risk prescribers. Results identified 1526 (4.0%) Florida, accounting 67% total 40% prescriptions. Relative lower-risk counterparts, they wrote sixteen times more prescriptions (79 vs. 5, p  Conclusions are disproportionately responsive state policies. However, opioids-prescribing remains highly concentrated among providers.