Potentiated antimicrobial medicaments

作者: Tibor Sipos

DOI:

关键词: AlcoholAntimicrobialAlkoxy groupSalicylanilidesPhenolSubstituentOrganic chemistryChemistryAlkylCarbanilides

摘要: Antimicrobial compositions are provided wherein there is obtained an enhancement of the activity antimicrobial agent exemplified by quaternary ammonium compounds, bisdiguanides, anti-fungal agents, phenols, hydroxydiphenyls, carbanilides, salicylanilides, organo-metallic antiseptics, antibiotics, halogens, organic halogen derivatives and iodophores derived from nonionic surface active agents polyvinylpyrrolidone combining with effective amount a potentiator. The potentiator alcohol or phenol derivative selected group consisting aliphatic straight branched chain primary, secondary tertiary monohydric alcohols have about 5 to 10 carbon atoms; up 17 atoms, their longest bonds having (b) cyclohexylalkanol alkylcyclohexylalkanol where alkanol as more fully defined hereinafter; (c) phenylalkanol, halophenylalkanol C1 C3 alkylphenylalkanol has 3 9 (d) cyclohexyl which may substituent on phenyl ring alkyl alkoxy, hydroxy, halo, amino dialkyl amino-substituents. Also topically topical medicament enhanced in (a), above. comprising potentiating suitable carrier useful for killing susceptible organisms various surfaces. novel find special applications surgical scrub solutions, use dressing wounds presence blood wound exudate would otherwise inhibit action if it were be used alone. invention application anesthetics, cell regulatory antimicrobials, anti-inflammatory compositions, like.

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