Effects of UDP-glucuronosyltransferase (UGT) polymorphisms on the pharmacokinetics of febuxostat in healthy Chinese volunteers.
作者： Meihua Lin , Jian Liu , Huili Zhou , Minglan Wu , Duo Lv
DOI: 10.1016/J.DMPK.2016.08.003
关键词: Pharmacology 、 Oral administration 、 Pharmacokinetics 、 Febuxostat 、 Heterozygote advantage 、 Linkage disequilibrium 、 Pharmacogenomics 、 Drug 、 Bioequivalence 、 Medicine
摘要: … role for UGT1A1 single nucleotide polymorphisms (SNPs) in … gene polymorphisms was further investigated in our study. … genetic polymorphisms in 42 healthy Chinese volunteers and …
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