Bacterial and osteoblast behavior on titanium, cobalt–chromium alloy and stainless steel treated with alkali and heat: A comparative study for potential orthopedic applications

作者: Xuefeng Hu , Koon Gee Neoh , Jieyu Zhang , En-Tang Kang

DOI: 10.1016/J.JCIS.2013.11.062

关键词: AnataseCobalt chromium alloyChemical engineeringUltraviolet irradiationAlkali metalTitaniumReactive oxygen speciesChemistryMetallurgyAdhesionOsteoblast

摘要: Abstract Hypothesis Anatase-modified titanium (Ti) substrates have been found to possess antibacterial properties in the absence of ultraviolet irradiation, but mechanism is not known. We hypothesize that this due bactericidal effects reactive oxygen species (ROS) generated by surface anatase. Experiments Alkali and heat treatment was used form anatase on Ti surface. The generation ROS, behavior bacteria osteoblasts anatase-modified were investigated. Cobalt–chrome (Co–Cr) alloys stainless steel (SS) similarly treated with alkali heat, their compared results obtained Ti. Findings anatase-functionalized demonstrated significant promoted apoptosis osteoblasts, likely a result ROS heat-treated Co–Cr SS also reduced bacterial adhesion bactericidal. This effect an increase hydrophilicity surfaces, no substrates. did induce thus these properties, they may be promising for orthopedic applications.

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