Impact of latent infection treatment in indigenous populations.

摘要: The aims of the present study were to identify risk factors associated with latent tuberculosis (TB), examine development active disease among contacts, and assess effectiveness treating infection in indigenous Brazilians from January 2006 December 2011. This was a retrospective consisting 1,371 392 whom underwent treatment for infection. Morbidity-from-TB data obtained Information System Disease Notification (SINAN) database, contacts’ collected clinical records using forms employed by Special Department Indigenous Health (SESAI) multidisciplinary teams, according SESAI’s instructions. variables that contacts age (odds ratio [OR]: 1.03; 95% confidence interval [CI]: 1.02–1.04) close contact smear-positive index case (OR: 2.26, CI: 1.59–3.22). TB tuberculin skin test (TST) ≥10 mm (relative [RR]: 1.12, 1.07–1.17), (RR: 1.01, 1.00–1.03), 0.03, 0.01–0.27). estimated number treatments needed prevent one 51 (95% 33–182). In TST mm, 10 6–19) necessary TB. Age Screening is high priority individuals contacting cases. are an effective measure control communities.