Nationwide analysis of adrenocortical carcinoma reveals higher perioperative morbidity in functional tumors.

摘要: Abstract Background Current adrenalectomy outcomes for functional adrenocortical carcinoma (ACC) remain unclear. This study examines nationwide in-hospital post-adrenalectomy ACC. Methods A retrospective analysis of the Nationwide Inpatient Sample database (2006–2011) to identify unilateral patients or nonfunctional ACC was performed. Patient demographics, comorbidities and postoperative were evaluated by t -test, Chi-square multivariate regression. Results Of 2199 who underwent adrenalectomy, 87% had 13% (86% hypercortisolism, 16% hyperaldosteronism, 4% hyperandrogenism). Functional significantly more comorbidities, experienced certain complications frequently including wound issues, insufficiency acute kidney injury with longer hospital stay compared (P  Conclusion Patients manifest significant complications. Such high-risk require appropriate preoperative medical optimization prior adrenalectomy. Synopsis have experience higher rates complications, hematoma formation, adrenal insufficiency, pulmonary embolism injury. also necessitate hospitalizations. These should undergo counseling in preparation