Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells

作者: Gabriel T. M. Lok , David W. Chan , Vincent W. S. Liu , Winnie W. Y. Hui , Thomas H. Y. Leung

DOI: 10.1371/JOURNAL.PONE.0023790

关键词: Cell growthCarcinogenesisBiologyMAPK/ERK pathwayOvarian cancerCancerCancer researchFOXM1MetastasisCancer cell

摘要: … To probe the oncogenic roles of FOXM1 in ovarian cancer, we assessed the functional effects of two active FOXM1 isoforms, FOXM1B and FOXM1C, on A2780cp and OVCA433 cells (…

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