Pregnancies in liver and kidney transplant recipients: a review of the current literature and recommendation

摘要: In this article, we focus on the biggest groups of organ transplant recipients, patients with a kidney or liver graft. Among these patients, about one sixth included women childbearing potential. Therefore, wish getting pregnant is frequent in peculiar and careful planning management pregnancies requires expertise obstetricians, midwives experts. Altogether, outcome acceptable. About 75% off all ended successfully live births, comparable if not superior to healthy women. This success might be caused only by special intensive care provided high-risk centres but also low rate unplanned pregnancies. The risk rejections loss after delivery 10%, it slightly enhanced recipients (LTRs) comparison graft (KTRs) number losses direct association pregnancy rare. However, there higher frequency pregnancy-associated disorders such as pre-eclampsia preterm an acceleration hypertension, new-onset diabetes mellitus newly arising infections favoured maintained immunosuppressive therapy. implies specialized 'control system' for that comprises ultrasound Doppler investigation assessment, infection screening, suitable therapy choice non-teratogenic immunosuppressives. Antihypertensive treatment must well balanced adjusted possible growth-retarding effect foetus co-morbidity mother. Finally, supplementation vitamin D iron much more important transplanted than deficiency anaemia are discussed have impact delivery. These claims widely discussed. Furthermore, current literature systematically reviewed Scopus analysis.