3 – Physiology Underlying Relationship of Epilepsy and Sleep

摘要: Publisher Summary The two main sleep states, non-rapid eye movement and rapid sleep, have different physiological components contrasting effects on generalized ictal interictal discharges. Injection of large dosages penicillin induces seizure manifestations primary epilepsy, particularly juvenile myoclonic epilepsy. Amygdala kindling provides the model a localization related Phasic events are thought to reflect aborted arousals brain stem processing intrinsic stimulation can be provoked by extrinsic stimulation, such as loud sound. During movement, spike-and-wave activity is rare occurs without clinical motor accompaniment. The mechanisms sleep-waking states some extent nonspecific with respect epileptic syndromes. Reduced cellular discharge chemical release in reticulothalamic pathways promote generation. most salient state specific affecting epilepsy degree which patterns synchronized alterations antigravity muscle tone. Rhythmic burst-pause firing generate synchronous synaptic actions, via spatial temporal summation, more likely augment magnitude spread excitatory inhibitory postsynaptic responses, including ones.