Principles of Antineoplastic Drug Development and Pharmacology

摘要: Principles of Drug Development Cancer Screening, Michael R. Grever The Human Tumor-Cloning Assay, Axel-R. Hanauske, Susan G. Hilsenbeck, and Daniel D. Von Hoff Phase I Clinical Trial Design, Rosemarie Mick New Approval Process: Regulatory Aspects, Renzo Canetta Biological Agents, Rosemary Mazanet, Mary Ann Foote, George Morstyn Antineoplastic Pharmacology Anticancer Drugs, B. W. Berry Charles Erlichman Pharmokinetics Pharmacodynamics, Mark J. Ratain Biochemical Modulation Chemotherapy, A. Sotos Carmen Allegra Interactions in Francois Lokiec Drug-Radiation Interactions, Everett E. Vokes Chemotherapy Interaction with Mario Sznol, Christine L. Carter Dan Longo Hematopoietic Growth Factors S. Gordon Dose Intensity, William M. Hryniuk Dosing Polymorphic Drug-Metabolizing Enzymes, Zhihong Lu Robert Diasio Cytochrome P-450, Frank Gonzalez Cellular Pharmacodynamics Peter O'Dwyer, Thomas C. Hamilton, Kang-Shen Yao, F. Ozols, James Gallo the Elderly, Maurice Schneider Children, Steven Weitman Barton Kamen Adaptive Control Dosage Regimens: Basic Concepts, Relevant Issues, Applications, Roger Jelliffe Individualized Alan V. Boddy Hilary Calvert Resistance Multidrug Resistance, Ahmad Safa DNA Topoisomerases Tumor Cell to Their Inhibitors, T. Beck Glutathione System Gerald Batist, Robyn Schecter, Moulay Alaoui-Jamali Importance Repair Eileen Dolan Antimetabolites, Godefridus Peters Gerrit Jansen Delivery Targeted Delivery, Pramod K. Gupta, John Cannon, Anil Kumar Tibrewal Intra-Arterial Ensminger Intraperitoneal Maurie Markman Intrathecal Blaney David Poplack Systemic Infusional Jacob Lokich Norwood Anderson Circadian Hrushesky, de Marsh, Patricia Wood