SPAK plays a pathogenic role in IgA nephropathy through the activation of NF-κB/MAPKs signaling pathway.
作者： Tsai-Jung Lin , Sung-Sen Yang , Kuo-Feng Hua , Yu-Ling Tsai , Shih-Hua Lin
DOI: 10.1016/J.FREERADBIOMED.2016.08.008
关键词: Immune system 、 NFKB1 、 T cell 、 Signal transduction 、 NF-κB 、 Cancer research 、 Immunoglobulin A 、 Biology 、 Proinflammatory cytokine 、 Mesangial cell 、 Immunology
摘要: … In this study, we used a model induced passively by injection of IgA and PnC, but this model … However, the mouse model still may represent IgAN in humans to a certain degree, as it …
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