Quantitation of hTERT mRNA Expression
作者： Christopher David Santini , Sheng-Yung Pai Chang
DOI:
关键词: Cancer 、 Molecular biology 、 Htert mrna 、 Telomerase reverse transcriptase 、 Messenger RNA 、 Biology
摘要: Methods and reagents for quantitating the expression of mRNA which encodes an active hTERT protein, is useful diagnosis prognosis cancer.
lens.org 参考文章(17)
David Bowtell, Andrzej Kilian, Vertebrate telomerase genes and proteins and uses thereof ,(1998)
David Tarin, Steve Goodison, Virginia Urquidi, Kenji Kitahara, Kenjiro Aogi, Comparison of Telomerase and CD44 Expression as Diagnostic Tumor Markers in Lesions of the Thyroid Clinical Cancer Research. ,vol. 5, pp. 2790- 2797 ,(1999)
Thomas R. Cech, Joachim Lingner, Telomerase catalytic subunit ,(1997)
Linda C. Giudice, Andrew R. Hoffman, Thanh H. Vu, Ji-Fan Hu, Gary A. Ulaner, Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts Cancer Research. ,vol. 58, pp. 4168- 4172 ,(1998)
Y. Cong, The Human Telomerase Catalytic Subunit hTERT: Organization of the Gene and Characterization of the Promoter Human Molecular Genetics. ,vol. 8, pp. 137- 142 ,(1999) , 10.1093/HMG/8.1.137
Yasuhiro Nakamura, Eiji Tahara, Hidetoshi Tahara, Wataru Yasui, Eiichi Tahara, Toshinori Ide, QUANTITATIVE REEVALUATION OF TELOMERASE ACTIVITY IN CANCEROUS AND NONCANCEROUS GASTROINTESTINAL TISSUES Molecular Carcinogenesis. ,vol. 26, pp. 312- 320 ,(1999) , 10.1002/(SICI)1098-2744(199912)26:4<312::AID-MC10>3.0.CO;2-A
N. Kim, M. Piatyszek, K. Prowse, C. Harley, M. West, P. Ho, G. Coviello, W. Wright, S. Weinrich, J. Shay, Specific association of human telomerase activity with immortal cells and cancer Science. ,vol. 266, pp. 2011- 2015 ,(1994) , 10.1126/SCIENCE.7605428
An Wu, Masamitsu Ichihashi, Masato Ueda, Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors. Cancer. ,vol. 86, pp. 2038- 2044 ,(1999) , 10.1002/(SICI)1097-0142(19991115)86:10<2038::AID-CNCR22>3.0.CO;2-A
H Hisatomi, K Nagao, T Kanamaru, H Endo, M Tomimatsu, K Hikiji, Levels of telomerase catalytic subunit mRNA as a predictor of potential malignancy. International Journal of Oncology. ,vol. 14, pp. 727- 759 ,(1999) , 10.3892/IJO.14.4.727
M. Wick, D. Zubov, G. Hagen, Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT) Gene. ,vol. 232, pp. 97- 106 ,(1999) , 10.1016/S0378-1119(99)00108-0