Attenuated Vaccine Against Fish Pathogen Francisella Sp.
作者： John Hawke , Esteban Soto
DOI:
关键词: Virology 、 Antigen 、 Pathogen 、 Francisella 、 Attenuated vaccine 、 Microbiology 、 Insertion 、 Tilapia 、 Gene 、 Mutant 、 Biology
摘要: An attenuated bacteria has been made by an insertion mutation in the iglC gene of Francisella asiatica , allelic exchange. The strain proved to be effective vaccine providing protection against infection F. tilapia, and is believed would at least partially immunize fish from other species . ΔiglC mutant can also serve as vectors present antigens pathogens fish, thereby serving vaccines well. In addition, a highly sensitive specific assay that used for identification developed.
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