Efficient ex vivo expansion of cd4+ and cd8+ t-cells from hiv infected subjects
作者： David N. Bell , Kenneth Lee Rosenthal
DOI:
关键词: Immunology 、 Immune system 、 Hiv infected 、 Biology 、 Hiv infected patients 、 Gene expression 、 Cytotoxic T cell 、 Ex vivo expansion 、 Cell 、 CD8 、 Virology
摘要: Methods for the expansion of CD4, CD8, and DP T-cells from HIV infected patients are disclosed which allow maintenance low levels HIV. The invention further discloses methods inhibition gene expression. Also rapid efficient screening cells derived HIV-infected to assess suitability various antiviral treatments. provides a means generation cell banks use in immune reconstitution treating or modifying expanded populations prior infusion enhance modulate therapeutic effectiveness.
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