Knowledge and practice on magnitude, diagnosis, treatment and prevention strategies of Hepatocellular Carcinoma in Ethiopia: A Systematic Review

摘要: Abstract Introduction: In Ethiopia, hepatocellular carcinoma (HCC) is the most common cancer with 100% fatality rate. HCC cases in low income countries die within few months following diagnosis. There lack of information on burden, risk factors, diagnosis modalities, surveillance strategies and treatment approaches to Ethiopia. Objective: To analyze existing evidence related strategies, prevention Ethiopia. Methods: All studies done Ethiopian irrespective year publication study types were included. Literatures retrieved from electronic database PubMedand Cochrane library during September/2016 January 2/2017. Key words mesh terms such as ‘hepatocellular carcinoma’, ‘hcc’, ‘hepatoma’, ‘malignant hepatoma’, ‘hepatocarcinoma’ used search for documents. Besides, we searched articles, guidelines reviews world health organizations, lancet Google scholar sites. Each was assessed by two authors inclusion based eligibility criteria, quality using critical appraisal checklist. Qualitative data synthesized analyzing theories studies. Medley reference manager manage citations. Results: A total 1448 literatures retrieved. Eight fulfill however, only three full-fledged articles. clinically characterized exhaustion, loss appetite, rapid weight, epigastric pain, right upper abdominal quadrant pain a rapidly growing mass, jaundice, ascites or without hepatomegaly splenomegaly. Data proportion among liver disease patients lies between 16.1%-19.2%. Cirrhosis followed hepatotoxic indigenous drugs viral hepatitis found be major factor HCC. there no activity standard staging systems. Furthermore, policy frame -work management HCC. Conclusion: As compared other countries, Ethiopia far behind addressing national framework guideline Moreover, neglected that considered death penalty community. Health professionals working facilities offices should share they have scientific community makers, further searching solutions informed decision, respectively. An intensified public strategy education early case detection importance. addition concerted effort made develop modality. [Ethiop. J. Dev. 2017;31(1):44-56] Key words: Hepatocellular Carcinoma,