作者: Neville M. Gibbs , William M. Weightman , Stephen A. Watts
DOI: 10.1097/ACO.0000000000000127
关键词: Antithrombotic 、 Intensive care medicine 、 Anticoagulant Agent 、 MEDLINE 、 Multidisciplinary assessment 、 Thrombotic risk 、 Relative risk 、 Ambulatory 、 Medicine 、 Perioperative 、 Anesthesiology and Pain Medicine
摘要: Purpose of review Many patients presenting for surgical or other procedures in an ambulatory setting are taking new antiplatelet anticoagulant agents. This assesses how the novel features these agents affect management antithrombotic therapy setting. Recent findings There have been very few studies investigating relative risks continuing ceasing reviews indicate that offer greater efficacy ease administration but more difficult to monitor reverse. They emphasize importance assessing bleeding risk procedure, thrombotic if agent is ceased, and patient factors increase likelihood bleeding. The timing cessation agent, required, depends on its pharmacokinetics patients' risks. Patients at high complications may require bridging therapy. Once agreed upon, perioperative plan should be made clear all involved. Summary As there clinical guide management, clinicians must make rational decisions relation requires knowledge their pharmacokinetics, a careful multidisciplinary assessment individual patients.