Effect of staphylococcal α-toxin on the phosphorylation of ADP by rat liver mitochondria—II
作者： E. Novák , J. Seifert , E. Buchar , H. Rašková
DOI: 10.1016/0041-0101(71)90134-6
关键词: Phosphate 、 Phosphorylation 、 Chemistry 、 Biochemistry 、 Inhibitory postsynaptic potential 、 Mitochondrion 、 Rat liver mitochondria 、 Respiratory chain 、 Electron transfer 、 Electron transport chain 、 Toxicology
摘要: Abstract The partially purified staphylococcal α-toxin inhibited phosphorylation of ADP coupled to electron transfer in NAD—ferricytochrome c; flavoprotein—K3Fe(CN)6 and ferrocytochrome c—oxygen segments the respiratory chain. phosphorylation, as determined by ratio phosphate esterified electrons transferred appeared be very sensitive inhibitory action toxin, while rate even increased. In addition, caused complete loss c absorbancy. This effect depends on presence mitochondria.
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