40 – Gastrointestinal Motility

作者: Michael G. Sarr , Joseph J. Cullen , Mary F. Otterson

DOI: 10.1016/B978-012655330-7/50042-3

关键词: Calcium in biologyGastric emptyingStomachIntracellularCalciumLarge intestineGastroenterologySmooth muscle contractionMotilityBiologyInternal medicineCell biology

摘要: This chapter discusses the physiology of smooth muscle contraction gut, with special reference to aspects techniques measure contractile activity. Gastrointestinal (GI) motility depends on presence activity within gut create forces that move intestinal content distally (or proximally during vomiting). One might choose either directly or indirectly, movement/transit luminal out stomach (gastric emptying), through small and/or large intestine (intestinal transit), and finally its discharge from (defecation). GI ultimately contractions generate force needed intraluminal along gut. The final common pathway intracellular release calcium. Once liberated, calcium induces mechanisms controlling interaction proteins leading cell shortening.

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